Which type of data is qualitative data?
Let us give an example using our online server for real biological systems that were studied using experimental methods:
Use AI preliminary research to obtain Experiment data Prognosis.
The correlation level between the forecast and the experimental results is shown in the graphs:
Data Table of Calculated and Experimental Data for Several Mutations in Alpha Synuclein, with Correlation Levels Indicated: R=-0.85, R=-0.96, R=-0.97 between correlation and Experimental Data.
The obtained correlation graphs for p53 protein.
Correlation graphs between experimental and calculated dates:
Choosing our online server You will receive a preliminary data meaning with a description and value of the quantities, their physical interpretation for a given molecular biological entity.
What should we do first to get a forecast for the experimental data?
First of all, this is the calculation of the potential energy of interaction between amino acid residues, visually this can be represented as a heat map or Excel tables.
Next, the calculation of the physical parameters of interaction, which are listed below in the figures, is the entropy change,enthalpy change,stability criterion,calculated dissociation constantsthe value of change in potential dissociation energy.
In addition, you can also take into account the experimental conditions:
1.temperature,
2.salt solutions,
3. denaturing solutions.
How to get a preliminary analysis?
You can make an order for calculating the effect of selected mutations in the target protein on the affinity of a dimer, tetramer, binding to an antibody or inhibitor.
You are required to specify the PDB file of the protein, or only the amino acid sequence, and then we will assemble the protein from the domains ourselves, specify the numbers and names of the substitutions, list the interactions with other molecules that interest you.
